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Butein tetramethyl ether

Product Specifications

CAS Number

155048-06-9

Target

BCRP

Related Pathways

Membrane transporter/Ion channel

Bioactivity

Butein tetramethyl ether (Compound 20) is a potent and selective inhibitor of breast cancer resistance protein / ATP-binding cassette sub-family G member 2 (BCRP/ABCG2) . It inhibits MCF-7 MX and MDCKBCRP cells with IC50 values of 2.2 μM and 1.03 μM, respectively. Butein tetramethyl ether holds potential for cancer research.

Smiles

C(/C=C/C1=CC(OC)=C(OC)C=C1)(=O)C2=C(OC)C=C(OC)C=C2

Molecular Formula

C19H20O5

Molecular Weight

328.359

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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