SBI-0087702
Product Specifications
CAS Number
864431-36-7
Target
PKC
Related Pathways
Chromatin/Epigenetic, Cytoskeletal Signaling
Bioactivity
SBI-0087702 enhances the cytoplasmic localization of ATF2 in melanoma cells. Induced translocation of ATF2 by SBI-0087702 to the mitochondria results in the loss of mitochondrial membrane integrity, thereby increasing apoptosis. Additionally, SBI-0087702 inhibits the growth and motility of melanoma cells. It also suppresses the phosphorylation of ATF2 at the Thr52 site by PKCε.
Smiles
O(C1=CC=C(C=C1)CCNCC2=CC=C(OC)C=3C=CC=CC32)C
Molecular Formula
C21H23NO2
Molecular Weight
321.413
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
LS122945-20ug 20 µg
C14orf148 (NOXRED1) (NM_001113475) Human Over-expression Lysate
Sign In for Pricing
View Details 
366845-01 50 µL
Natriuretic Peptide Receptor C (Atrial Natriuretic Peptide Receptor 3, Atrial Natriuretic Peptide Clearance Receptor, Atrial Natriuretic Peptide Receptor Type C, ANP-C, ANPR-C, NPR-C, NPR3, ANPRC, C5orf23, NPRC)
Sign In for Pricing
View Details 366845-02 200 µL
Natriuretic Peptide Receptor C (Atrial Natriuretic Peptide Receptor 3, Atrial Natriuretic Peptide Clearance Receptor, Atrial Natriuretic Peptide Receptor Type C, ANP-C, ANPR-C, NPR-C, NPR3, ANPRC, C5orf23, NPRC)
Sign In for Pricing
View Details 