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SBI-0087702

Product Specifications

CAS Number

864431-36-7

Target

PKC

Related Pathways

Chromatin/Epigenetic, Cytoskeletal Signaling

Bioactivity

SBI-0087702 enhances the cytoplasmic localization of ATF2 in melanoma cells. Induced translocation of ATF2 by SBI-0087702 to the mitochondria results in the loss of mitochondrial membrane integrity, thereby increasing apoptosis. Additionally, SBI-0087702 inhibits the growth and motility of melanoma cells. It also suppresses the phosphorylation of ATF2 at the Thr52 site by PKCε.

Smiles

O(C1=CC=C(C=C1)CCNCC2=CC=C(OC)C=3C=CC=CC32)C

Molecular Formula

C21H23NO2

Molecular Weight

321.413

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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