What is the catalog number for EGFR-IN-140?

The catalog number for EGFR-IN-140 is T204256.

What sizes are available for EGFR-IN-140?

EGFR-IN-140 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does EGFR-IN-140 come in?

EGFR-IN-140 is available in 2 different pack sizes.

Is EGFR-IN-140 in stock?

EGFR-IN-140 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures EGFR-IN-140?

EGFR-IN-140 is manufactured by Molfinity.

What is the estimated delivery time for EGFR-IN-140?

Estimated delivery time for EGFR-IN-140 is approximately 10 business day(s), depending on your location.

EGFR-IN-140

Product Specifications

Target

EGFR

Related Pathways

Tyrosine Kinase/Adaptors, Angiogenesis, JAK/STAT signaling

Bioactivity

EGFR-IN-140 (Compound 31) is an inhibitor of EGFR, effectively targeting both wild-type EGFR and the EGFRL858R/T790M/C797S mutant, with Ki values of 0.95 nM and 2.1 nM, respectively. Additionally, it inhibits EGFRdel19/T790M/C797S in Ba/F3 cells with an IC50 of 56.9 nM and demonstrates antitumor activity in mouse models.