PI3K?/BET-IN-1
Product Specifications
CAS Number
3054869-10-9
Target
Epigenetic Reader Domain|||PI3K
Related Pathways
PI3K/Akt/mTOR signaling|||Chromatin/Epigenetic
Bioactivity
PI3K?/BET-IN-1 (compound 10b) exhibits excellent and balanced activity against PI3K? (IC50= 112 nM) and BRD4-BD1 (IC50= 19 nM), while also demonstrating strong antiproliferative effects in DLBCL cells.
Smiles
O=C1C=2NC=CC2C(=CN1C)C3=NC=4C=C(SC4C(=N3)N5CCOCC5)CN6CCC(CC6)C(O)(C)C
Molecular Formula
C27H34N6O3S
Molecular Weight
522.662
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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