ADS1017
Product Specifications
Target
Histamine Receptor, AChR
Related Pathways
GPCR/G Protein, Immunology/Inflammation, Neuroscience
Bioactivity
ADS1017 is an antagonist of histamine receptor (histamine receptor) and muscarinic receptor (muscarinic receptor), displaying strong affinity for hH3R, hH4R, hM2R, and hM4R with pKi values of 6.8, 5.5, 7.4, and 7.2, respectively. In mouse models of pain induced by Capsaicin or Oxaliplatin, ADS1017 exhibits analgesic and anti-hyperalgesic effects.
Smiles
C1CN(CCN1CCCCCCCOC2=CC=CC=C2)CCCCN(CC3=CC=CC=C3)C(=N)N
Molecular Formula
C29H45N5O
Molecular Weight
479.701
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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