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ADS1017

Product Specifications

Target

Histamine Receptor|||AChR

Related Pathways

GPCR/G Protein|||Immunology/Inflammation|||Neuroscience

Bioactivity

ADS1017 is an antagonist of histamine receptor (histamine receptor) and muscarinic receptor (muscarinic receptor), displaying strong affinity for hH3R, hH4R, hM2R, and hM4R with pKi values of 6.8, 5.5, 7.4, and 7.2, respectively. In mouse models of pain induced by Capsaicin or Oxaliplatin, ADS1017 exhibits analgesic and anti-hyperalgesic effects.

Smiles

C1CN(CCN1CCCCCCCOC2=CC=CC=C2)CCCCN(CC3=CC=CC=C3)C(=N)N

Molecular Formula

C29H45N5O

Molecular Weight

479.701

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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