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EGFR-IN-142

Product Specifications

Target

EGFR

Related Pathways

JAK/STAT signaling, Tyrosine Kinase/Adaptors, Angiogenesis

Bioactivity

EGFR-IN-142 (compound 9a) is an EGFR inhibitor with an IC50 value of 0.08 μM. It exhibits antiproliferative activity against MCF-7 cells (IC50 = 3.31 μM) and WI-38 cells (IC50 = 43.99 μM) .

Smiles

C1=CC=C(C=C1)CSC2=NN=C(S2)NC(=O)CSC3=NN=C(S3)SCC(=O)NC4=NN=C(S4)SCC5=CC=CC=C5

Molecular Formula

C24H20N8O2S7

Molecular Weight

676.923

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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