Flonoltinib sulfate

Product Specifications

CAS Number

2568842-57-7

Target

Apoptosis|||FLT|||JAK

Related Pathways

Chromatin/Epigenetic|||Angiogenesis|||Tyrosine Kinase/Adaptors|||JAK/STAT signaling|||Apoptosis|||Stem Cells

Bioactivity

Flonoltinib maleate is an orally active dual inhibitor of JAK2/FLT3, with IC50 values of 0.7 nM for JAK2, 4 nM for FLT3, 26 nM for JAK1, and 39 nM for JAK3. It exhibits anticancer properties.

Smiles

O=S(=O)(O)O.FC1=CC(=CC=C1N2CCC(N(C)CCO)CC2)NC=3N=CC(=C(N3)C=4C=NN(C4)C(C)C)C

Molecular Formula

C25H36FN7O5S

Molecular Weight

565.661

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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