Flonoltinib sulfate
Product Specifications
CAS Number
2568842-57-7
Target
Apoptosis|||FLT|||JAK
Related Pathways
Chromatin/Epigenetic|||Angiogenesis|||Tyrosine Kinase/Adaptors|||JAK/STAT signaling|||Apoptosis|||Stem Cells
Bioactivity
Flonoltinib maleate is an orally active dual inhibitor of JAK2/FLT3, with IC50 values of 0.7 nM for JAK2, 4 nM for FLT3, 26 nM for JAK1, and 39 nM for JAK3. It exhibits anticancer properties.
Smiles
O=S(=O)(O)O.FC1=CC(=CC=C1N2CCC(N(C)CCO)CC2)NC=3N=CC(=C(N3)C=4C=NN(C4)C(C)C)C
Molecular Formula
C25H36FN7O5S
Molecular Weight
565.661
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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