UCB9386
Product Specifications
Target
AMPK|||JAK
Related Pathways
Tyrosine Kinase/Adaptors|||Chromatin/Epigenetic|||Angiogenesis|||PI3K/Akt/mTOR signaling|||JAK/STAT signaling|||Stem Cells
Bioactivity
UCB9386 is a brain-penetrant and selective inhibitor of Nuak1, with a pIC50 of 10.1. It also inhibits Nuak2 and Kak2, showing approximately 50% inhibition at 10 nM.
Smiles
C[C@H](C1=CC=CC=C1)N2C3=CC(=NC=C3N=C(C2=O)N4CC5(C4)CN(C5)C)C6=CN=C7N6N=CC=C7
Molecular Formula
C27H26N8O
Molecular Weight
478.548
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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