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UCB9386

Product Specifications

Target

AMPK, JAK

Related Pathways

Tyrosine Kinase/Adaptors, Chromatin/Epigenetic, Angiogenesis, PI3K/Akt/mTOR signaling, JAK/STAT signaling, Stem Cells

Bioactivity

UCB9386 is a brain-penetrant and selective inhibitor of Nuak1, with a pIC50 of 10.1. It also inhibits Nuak2 and Kak2, showing approximately 50% inhibition at 10 nM.

Smiles

C[C@H](C1=CC=CC=C1)N2C3=CC(=NC=C3N=C(C2=O)N4CC5(C4)CN(C5)C)C6=CN=C7N6N=CC=C7

Molecular Formula

C27H26N8O

Molecular Weight

478.548

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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