HAChE/hBuChE/GSK-3β-IN-1
Product Specifications
Target
GSK-3, Cholinesterase (ChE)
Related Pathways
Stem Cells, PI3K/Akt/mTOR signaling, Neuroscience
Bioactivity
HAChE/hBuChE/GSK-3β-IN-1 (Compound 6c) is a multi-target compound designed for Alzheimer's treatment capable of crossing the blood-brain barrier. It inhibits hAChE with an IC50 of 28.88 nM, hBuChE with an IC50 of 131.90 nM, and GSK-3β with an IC50 of 51.42 nM. Additionally, it acts as an inhibitor of tau protein and Aβ protein aggregation.
Smiles
COC1=CC=C(C=C1)C(=O)/C=C/NC2=CC3=C(C=C2)OC(=O)C=C3
Molecular Formula
C19H15NO4
Molecular Weight
321.327
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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