CDK2/9-IN-1
Product Specifications
CAS Number
2222285-23-4
Target
Apoptosis|||CDK
Related Pathways
Apoptosis|||Cell Cycle/Checkpoint
Bioactivity
CDK2/9-IN-1 (compound 20a) is an orally active dual inhibitor of CDK2 and CDK9, with IC50 values of 0.004 ?M and 0.009 ?M for CDK2 and CDK9, respectively. It induces apoptosis by regulating G2/M cell cycle arrest and exhibits antitumor activity.
Smiles
O=S(=O)(N)C1=CC=C(C=C1)NC2=NC=C(C(=N2)NC3=NC=CS3)C
Molecular Formula
C14H14N6O2S2
Molecular Weight
362.43
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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