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CDK2/9-IN-1

Product Specifications

CAS Number

2222285-23-4

Target

Apoptosis|||CDK

Related Pathways

Apoptosis|||Cell Cycle/Checkpoint

Bioactivity

CDK2/9-IN-1 (compound 20a) is an orally active dual inhibitor of CDK2 and CDK9, with IC50 values of 0.004 ?M and 0.009 ?M for CDK2 and CDK9, respectively. It induces apoptosis by regulating G2/M cell cycle arrest and exhibits antitumor activity.

Smiles

O=S(=O)(N)C1=CC=C(C=C1)NC2=NC=C(C(=N2)NC3=NC=CS3)C

Molecular Formula

C14H14N6O2S2

Molecular Weight

362.43

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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