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M351-0056

Product Specifications

CAS Number

1189495-81-5

Bioactivity

M351-0056 is an agonist of the immune checkpoint protein VISTA, diminishing cytokine secretion induced by VISTA, enhancing VISTA-induced T cell proliferation, and exhibiting immunomodulatory activity. Additionally, M351-0056 has been shown to improve psoriasis-like dermatitis induced by Imiquimod in mouse models.

Smiles

O=S(=O)(NC1=CC=C(Br)C=C1F)C=2C=C(SC2C)C=3N=C(SC3)C

Molecular Formula

C15H12BrFN2O2S3

Molecular Weight

447.365

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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