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ABCG2-IN-4

Product Specifications

CAS Number

2559759-63-4

Target

BCRP

Related Pathways

Membrane transporter/Ion channel

Bioactivity

ABCG2-IN-4 (Compound K31) is an orally active ABCG2 inhibitor that reduces the release of Protoporphyrin IX (PPIX) from red blood cells into the plasma and prevents phototoxicity. In mouse models, ABCG2-IN-4 also demonstrates anti-inflammatory and antioxidant properties.

Smiles

C(C(C)C)[C@H]1C2=C(C=3C(N2)=CC(OC)=CC3)C[C@@]4(N1C(=O)[C@H](CC(NC(C)C)=O)NC4=O)[H]

Molecular Formula

C24H32N4O4

Molecular Weight

440.535

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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