ABCG2-IN-4
Product Specifications
CAS Number
2559759-63-4
Target
BCRP
Related Pathways
Membrane transporter/Ion channel
Bioactivity
ABCG2-IN-4 (Compound K31) is an orally active ABCG2 inhibitor that reduces the release of Protoporphyrin IX (PPIX) from red blood cells into the plasma and prevents phototoxicity. In mouse models, ABCG2-IN-4 also demonstrates anti-inflammatory and antioxidant properties.
Smiles
C(C(C)C)[C@H]1C2=C(C=3C(N2)=CC(OC)=CC3)C[C@@]4(N1C(=O)[C@H](CC(NC(C)C)=O)NC4=O)[H]
Molecular Formula
C24H32N4O4
Molecular Weight
440.535
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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