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Polθ-IN-7

Product Specifications

CAS Number

2923356-52-7

Target

DNA/RNA Synthesis

Related Pathways

DNA Damage/DNA Repair, Cell Cycle/Checkpoint

Bioactivity

Polθ-IN-7 (example 12) is an inhibitor of DNA polymerase θ (Polθ) with a Ki of 1.27 nM.

Smiles

O=C1[C@]2(N(C(=O)C[C@@]2(CN(CCN3CCN(C)CC3)C=4C(N1C)=CC=CC4C)[H])C5=CC(C(F)(F)F)=CC(C)=N5)[H]

Molecular Formula

C28H35F3N6O2

Molecular Weight

544.612

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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