SMase-IN-1
Product Specifications
CAS Number
33017-85-5
Target
Cholinesterase (ChE), Phospholipase, Antibacterial
Related Pathways
Neuroscience, Metabolism, Microbiology/Virology
Bioactivity
SMase-IN-1 (Compound 4) is a bacterial sphingomyelinase (SMase) inhibitor with an IC50 value of 6.43 μM against Bacillus cereus SMase. It also inhibits eqBuChE with an inhibition rate of 59.50% at a concentration of 50 μM. SMase-IN-1 forms a complex with Cu2+ through bio-metal interactions and can inhibit hemolysis of sheep red blood cells induced by Bacillus cereus.
Smiles
O=C1NC(=S)NC2=CC=C(Cl)C=C12
Molecular Formula
C8H5ClN2OS
Molecular Weight
212.656
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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