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SMase-IN-1

Product Specifications

CAS Number

33017-85-5

Target

Cholinesterase (ChE) |||Phospholipase|||Antibacterial

Related Pathways

Neuroscience|||Metabolism|||Microbiology/Virology

Bioactivity

SMase-IN-1 (Compound 4) is a bacterial sphingomyelinase (SMase) inhibitor with an IC50 value of 6.43 µM against Bacillus cereus SMase. It also inhibits eqBuChE with an inhibition rate of 59.50% at a concentration of 50 µM. SMase-IN-1 forms a complex with Cu2+ through bio-metal interactions and can inhibit hemolysis of sheep red blood cells induced by Bacillus cereus.

Smiles

O=C1NC(=S)NC2=CC=C(Cl)C=C12

Molecular Formula

C8H5ClN2OS

Molecular Weight

212.656

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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