What is the catalog number for LSD1-IN-38?

The catalog number for LSD1-IN-38 is T204124.

What sizes are available for LSD1-IN-38?

LSD1-IN-38 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does LSD1-IN-38 come in?

LSD1-IN-38 is available in 2 different pack sizes.

Is LSD1-IN-38 in stock?

LSD1-IN-38 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures LSD1-IN-38?

LSD1-IN-38 is manufactured by Molfinity.

What is the estimated delivery time for LSD1-IN-38?

Estimated delivery time for LSD1-IN-38 is approximately 10 business day(s), depending on your location.

LSD1-IN-38

Product Specifications

Target

Histone Demethylase

Related Pathways

Chromatin/Epigenetic

Bioactivity

LSD1-IN-38 (Compound 23e) is a reversible, orally active inhibitor of lysine-specific demethylase 1 (LSD1), with an IC50 of 1.2 nM. It effectively inhibits the proliferation of cancer cells MV4-11, Kasumi-1, and NCI-H526 with IC50 values of 5, 4, and 11 nM, respectively. Furthermore, LSD1-IN-38 activates CD86 expression with an EC50 of 0.034 μM and induces differentiation in MV4-11 cells. In mouse models, this compound demonstrates antitumor activity.