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BChE-IN-39

Product Specifications

Target

Cholinesterase (ChE)

Related Pathways

Neuroscience

Bioactivity

BChE-IN-39 (Compound 7c) selectively inhibits butyrylcholinesterase (BChE) with an IC50 of 0.08 μM, while showing an IC50 of 3.98 μM for acetylcholinesterase (AChE) inhibition. Additionally, BChE-IN-39 downregulates GSK-3β expression, thereby inhibiting the excessive phosphorylation of tau protein.

Smiles

C1=CC=C2C(=C1)C(=O)N(C2=O)CC3=CC=C(C=C3)C(=O)NCC4=C[N+](=CC=C4)CC5=CC(=CC=C5)F.[Cl-]

Molecular Formula

C29H23ClFN3O3

Molecular Weight

515.963

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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