AChE/BuChE-IN-6
Product Specifications
Target
Cholinesterase (ChE)
Related Pathways
Neuroscience
Bioactivity
AChE/BuChE-IN-6 (Compound 11f) is an inhibitor of AChE and BuChE, with IC50 values of 1.24 and 1.85 ?g/mL, respectively. It exhibits strong DPPH radical scavenging activity (IC50 = 3.15 ?g/mL) . In vivo toxicity studies demonstrate that AChE/BuChE-IN-6 is safe, showing no significant differences in blood and biochemical parameters compared to controls, and no abnormalities in liver and kidney tissues. This compound shows potential for Alzheimer's disease research.
Smiles
CC1=CC=C(C=C1)C2=C(C=NN2)C3=C(C=CC(=C3)OCC(=O)NC4=CC=C(C=C4)Cl)O
Molecular Formula
C24H20ClN3O3
Molecular Weight
433.887
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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