Thrombin inhibitor 13
Product Specifications
Target
Thrombin
Related Pathways
Proteases/Proteasome
Bioactivity
Thrombin inhibitor 13 (Compound 13a) acts as a covalent reversible inhibitor of thrombin (thrombin, FIIa) with an IC50 of 0.7 nM. This compound prolongs activated partial thromboplastin time (aPTT) and prothrombin time (PT), demonstrating both antithrombotic and anticoagulant properties.
Smiles
CC(C)(C)C(=O)N1C(=NC(=N1)C2=NC=CN=C2)NCC3=CC=C(S3)Cl
Molecular Formula
C16H17ClN6OS
Molecular Weight
376.864
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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