ND-L11B free base

Product Specifications

Target

Histone Methyltransferase

Related Pathways

Chromatin/Epigenetic

Bioactivity

ND-L11B is an effective degrader of the nuclear receptor binding SET domain protein 2 (NSD2) and RE-IIBP, with DC50 values of 1.48 ?M and 0.8 ?M, respectively, and a Dmax close to 80%.

Smiles

NC(N=CN=C12)=C1N=CN2CC3=CC(C4=CC(OCC(NCCCCCCCCCCCN)=O)=C(F)C=C4)=NC=C3N5C[C@](CC(F)F)(N)CCC5

Molecular Formula

C37H51F3N10O2

Molecular Weight

724.862

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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