ND-L11B free base
Product Specifications
Target
Histone Methyltransferase
Related Pathways
Chromatin/Epigenetic
Bioactivity
ND-L11B is an effective degrader of the nuclear receptor binding SET domain protein 2 (NSD2) and RE-IIBP, with DC50 values of 1.48 ?M and 0.8 ?M, respectively, and a Dmax close to 80%.
Smiles
NC(N=CN=C12)=C1N=CN2CC3=CC(C4=CC(OCC(NCCCCCCCCCCCN)=O)=C(F)C=C4)=NC=C3N5C[C@](CC(F)F)(N)CCC5
Molecular Formula
C37H51F3N10O2
Molecular Weight
724.862
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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