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ZG297

Product Specifications

CAS Number

2999673-52-6

Target

Antibiotic, Antibacterial

Related Pathways

Microbiology/Virology

Bioactivity

ZG297 is an agonist of Staphylococcus aureus ClpP (SaClpP) with an EC50 of 0.26 μM. It degrades SaFtsZ and inhibits bacterial cell division, exhibiting antistaphylococcal activity by inhibiting S. aureus 8325-4 and MRSA strains, with a MIC range of 0.063-256 μg/mL. In mouse models, ZG297 demonstrates anti-infective properties.

Smiles

C(NCCCC(F)(F)F)(=O)N1[C@@]2(N([C@@]([C@H](CC)C)(C(=O)N(CC3=C4C(=C5C(=C3)C=CC=C5)C=CC=C4)C2)[H])C(=O)CC1)[H]

Molecular Formula

C31H35F3N4O3

Molecular Weight

568.63

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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