ZG297
Product Specifications
CAS Number
2999673-52-6
Target
Antibiotic, Antibacterial
Related Pathways
Microbiology/Virology
Bioactivity
ZG297 is an agonist of Staphylococcus aureus ClpP (SaClpP) with an EC50 of 0.26 μM. It degrades SaFtsZ and inhibits bacterial cell division, exhibiting antistaphylococcal activity by inhibiting S. aureus 8325-4 and MRSA strains, with a MIC range of 0.063-256 μg/mL. In mouse models, ZG297 demonstrates anti-infective properties.
Smiles
C(NCCCC(F)(F)F)(=O)N1[C@@]2(N([C@@]([C@H](CC)C)(C(=O)N(CC3=C4C(=C5C(=C3)C=CC=C5)C=CC=C4)C2)[H])C(=O)CC1)[H]
Molecular Formula
C31H35F3N4O3
Molecular Weight
568.63
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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