GDC-2992
Product Specifications
CAS Number
2753651-10-2
Target
Androgen Receptor|||PROTACs
Related Pathways
Endocrinology/Hormones|||PROTAC
Purity
0.9982
Bioactivity
GDC-2992 is a selective and orally active androgen receptor (AR) degradator that degrades AR (DC50 = 2.7 nM) and inhibits proliferation (IC50 = 9.7 nM) in VCaP cells, making it suitable for studying castration-resistant prostate cancer (CRPC) .
Smiles
O([C@H]1C(C)(C)[C@H](NC(=O)C2=CC=C(C=C2)N3CCC(CN4CCN(CC4)C=5C=C6C(=CC5)C(=O)N(N=C6)[C@@H]7C(=O)NC(=O)CC7)CC3)C1(C)C)C8=CC(Cl)=C(C#N)C=C8
Molecular Formula
C45H51ClN8O5
Molecular Weight
819.39
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
GTR15249971 1 Vial
Lentiviral mouse Wdr59 shRNA (UAS) - Lentiviral mouse Wdr59 shRNA (UAS, RFP) (25)
Ask
View Details 
GTR15295868 1 Vial
Lentiviral mouse Cp shRNA (UAS) - Lentiviral mouse Cp shRNA (UAS) (25)
Ask
View Details 
MBS6184022-01 0.1 mL
SERPINA6 (Serpin Peptidase Inhibitor, Clade A (alpha-1 Antiproteinase, Antitrypsin), Member 6, CBG) (PE)
Ask
View Details MBS6184022-02 5x 0.1 mL
SERPINA6 (Serpin Peptidase Inhibitor, Clade A (alpha-1 Antiproteinase, Antitrypsin), Member 6, CBG) (PE)
Ask
View Details