JRD-SIK1/2i-4
Product Specifications
CAS Number
2810810-00-3
Target
Interleukin|||SIK|||TNF
Related Pathways
Apoptosis|||PI3K/Akt/mTOR signaling|||Immunology/Inflammation
Bioactivity
JRD-SIK1/2i-4 is a SIK1/2 inhibitor that induces nuclear translocation of CRTC3 at low micromolar concentrations. It is expected to saturate SIK1 and SIK2, but not SIK3.
Smiles
N#CC=1N=CC(OC2CN(C)C2)=C(C1)C=3C=CN4N=C(C=C4C3)NC(=O)C5CC5
Molecular Formula
C21H20N6O2
Molecular Weight
388.42
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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