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TLR8 antagonist-1

Product Specifications

CAS Number

1111460-83-3

Target

TLR|||NF-?B|||MyD88

Related Pathways

Immunology/Inflammation|||NF-?B

Bioactivity

TLR8 antagonist 1 (Compound 10) is a selective antagonist that can inhibit TLR8 mediated inflammation and signaling pathways. TLR8 antagonist 1 reduces MyD88 recruitment and inhibits NF - ? B and IRF pathways, exhibiting certain anti-inflammatory activity.

Smiles

O=C(NC1CCN(CC)CC1)C2=CC=C(OCC=3C(=NOC3C)C)C(OC)=C2

Molecular Formula

C21H29N3O4

Molecular Weight

387.47

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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