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Pomalidomide-PEG5-Alkyne

Product Specifications

Target

Ligands for Target Protein for PROTAC

Related Pathways

PROTAC

Bioactivity

Pomalidomide-PEG5-Alkyne serves as a key building block in the synthesis of targeted protein degraders and PROTACs. This compound includes a (CRBN) -recruiting ligand and a PEGylated crosslinker that features a pendant alkyne, which facilitates click chemistry reactions with an azide on the target ligand.

Smiles

C#CCOCCOCCOCCOCCOCCC(NC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O)=O

Molecular Formula

C27H33N3O10

Molecular Weight

559.57

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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