GC-072
Product Specifications
CAS Number
1371629-36-5
Target
Others
Related Pathways
Others
Bioactivity
GC-072 is a potent 4-oxoquinolizine antibiotic that selectively inhibits bacterial topoisomerase. It shows in vitro activity against both sensitive and resistant strains of B. pseudomallei, and it is also effective against other dangerous pathogens such as Burkholderia mallei, Bacillus anthracis, Yersinia pestis, and Francisella tularensis. In a murine model of melioidosis, oral administration of GC-072 demonstrated dose-dependent survival benefits, indicating its potential as a first-line oral treatment option for melioidosis.
Smiles
O=C(O)C1=CC(=C2C(=C(C=CN2C1=O)C=3C=C(F)C(N)=CC3F)C)C4CC4
Molecular Formula
C20H16F2N2O3
Molecular Weight
370.35
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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