Tubulin polymerization-IN-71
Product Specifications
Target
Apoptosis, Microtubule Associated
Related Pathways
Apoptosis, Cytoskeletal Signaling
Bioactivity
Tubulin polymerization-IN-71 (Compound 4k) is an inhibitor of tubulin polymerization with an IC50 of 3.06 μM. It suppresses the proliferation of cancer cells MG-63 and U2OS, with an IC50 ranging from 0.08 to 0.14 μM. Additionally, Tubulin polymerization-IN-71 induces cell cycle arrest at the G2/M phase and triggers apoptosis in MG-63 cells.
Molecular Formula
C25H24FNO8
Molecular Weight
485.46
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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