Tubulin polymerization-IN-71
Product Specifications
Target
Apoptosis|||Microtubule Associated
Related Pathways
Apoptosis|||Cytoskeletal Signaling
Bioactivity
Tubulin polymerization-IN-71 (Compound 4k) is an inhibitor of tubulin polymerization with an IC50 of 3.06 ?M. It suppresses the proliferation of cancer cells MG-63 and U2OS, with an IC50 ranging from 0.08 to 0.14 ?M. Additionally, Tubulin polymerization-IN-71 induces cell cycle arrest at the G2/M phase and triggers apoptosis in MG-63 cells.
Molecular Formula
C25H24FNO8
Molecular Weight
485.46
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Product Datasheet
https://www.targetmol.com/attachment/DataSheet/296282250507452476/T203659
Available Sizes
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