USP7-IN-16
Product Specifications
CAS Number
2166587-77-3
Target
Others, DUB
Related Pathways
DNA Damage/DNA Repair, Cell Cycle/Checkpoint, Others, Ubiquitination
Bioactivity
USP7-IN-16 (Compound 61) is a selective inhibitor of USP7, with IC50 values of 5.5 nM in the FLINT assay and 2.1 nM in MM.1S cells. This compound exhibits antitumor activity in mice and holds potential for research in the field of oncology.
Smiles
O=C1C2=C(N(C=C2)C3=CC(OC)=CC(OC)=C3)N=CN1CC4(O)CCN(C(=O)[C@H]5[C@@H](CN(C(=O)C=6SC(=NC6C)C=7C=CC(C)=NC7)CC5)C8=CC=CC=C8)CC4
Molecular Formula
C43H45N7O6S
Molecular Weight
787.93
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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