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USP7-IN-16

Product Specifications

CAS Number

2166587-77-3

Target

Others, DUB

Related Pathways

DNA Damage/DNA Repair, Cell Cycle/Checkpoint, Others, Ubiquitination

Bioactivity

USP7-IN-16 (Compound 61) is a selective inhibitor of USP7, with IC50 values of 5.5 nM in the FLINT assay and 2.1 nM in MM.1S cells. This compound exhibits antitumor activity in mice and holds potential for research in the field of oncology.

Smiles

O=C1C2=C(N(C=C2)C3=CC(OC)=CC(OC)=C3)N=CN1CC4(O)CCN(C(=O)[C@H]5[C@@H](CN(C(=O)C=6SC(=NC6C)C=7C=CC(C)=NC7)CC5)C8=CC=CC=C8)CC4

Molecular Formula

C43H45N7O6S

Molecular Weight

787.93

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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