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FXR agonist 10

Product Specifications

Target

FXR

Related Pathways

Metabolism

Bioactivity

FXR agonist10 (Compound 27) acts as an agonist for FXR with an EC50 of 14.26 ?M. It increases the expression of SHP and BSEP proteins while decreasing the expression of NTCP and CYP7A1 proteins. Additionally, FXR agonist10 has been shown to ameliorate ANIT-induced cholestasis in mouse models.

Molecular Formula

C15H22O4

Molecular Weight

266.33

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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