N-Ac-?-Calicheamicin-AcBut-NHS ester
Product Specifications
CAS Number
174885-02-0
Target
ADC Cytotoxin
Related Pathways
Antibody-drug Conjugate/ADC Related
Bioactivity
AcBut-N-Ac-?-Calicheamicin serves as a toxic molecule for ADCs, inducing cell cycle arrest and apoptosis (Apoptosis) by causing DNA double-strand breaks. Primarily utilized in the synthesis of antibody-drug conjugates (ADC), it holds promise for cancer research, particularly in studies related to acute lymphoblastic leukemia (ALL) and other hematological malignancies.
Molecular Formula
C77H99IN6O28S3
Molecular Weight
1779.73
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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