FXIa-IN-15
Product Specifications
CAS Number
3053222-76-4
Target
Factor Xa
Related Pathways
Metabolism
Bioactivity
FXIa-IN-15 (Compound (S) -10h) is an inhibitor of factor XIa (FXIa) and plasma kallikrein (PKa) with IC50 values of 0.38 nM and 59.2 nM, respectively. It exhibits anticoagulant properties by prolonging the 50% activated partial thromboplastin time (aPTT) with an EC1.5X of 0.55 ?M.
Smiles
O(C)C=1C(C2=C(C=CC(Cl)=C2)N3C=C(C(F)(F)F)N=N3)=CC(=O)N([C@@H](CC4=CC=CC=C4)C5=CN(N=N5)C6=CC=C(C(O)=O)C=C6)C1
Molecular Formula
C32H23ClF3N7O4
Molecular Weight
662.02
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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