Purine riboside-5'-O-triphosphate sodium
Product Specifications
CAS Number
35892-95-6
Target
DNA/RNA Synthesis, Nucleoside Antimetabolite/Analog, CaMK
Related Pathways
Cell Cycle/Checkpoint, DNA Damage/DNA Repair, Neuroscience
Bioactivity
Purine riboside-5'-O-triphosphate sodium is an active metabolite of Nebularine and acts as an inhibitor of DNA primase ATP and GTP polymerization activities, with IC50 values of 35 μM and 28 μM, respectively. It also inhibits calmodulin-dependent protein kinase II (CaMKII), with a Ki value of 590 μM.
Smiles
O[C@H]1[C@@H](O[C@@H]([C@H]1O)COP(OP(OP([O-])([O-])=O)([O-])=O)([O-])=O)N2C3=NC=NC=C3N=C2.[Na+].[Na+].[Na+].[Na+]
Molecular Formula
C10H11N4Na4O13P3
Molecular Weight
580.09
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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