IQ-1S
Product Specifications
CAS Number
1421610-21-0
Target
JNK
Related Pathways
MAPK
Bioactivity
IQ-1S is an inhibitor of NF-κB/activating protein 1 (AP-1) with an IC50 of 1.8 μM. It exhibits high binding affinity to all three JNKs, with Kd values for JNK3, JNK2, and JNK1 being 87 nM, 360 nM, and 390 nM, respectively.
Smiles
[O-]N=C1C2=C(C3=CC=CC=C13)N=C4C=CC=CC4=N2.[Na+]
Molecular Formula
C15H8N3NaO
Molecular Weight
269.23
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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