TGR5 agonist 7
Product Specifications
Target
GPCR19, Others
Related Pathways
Others, GPCR/G Protein
Bioactivity
TGR5 agonist 7 (Compound 22-Na) is an intestine-restricted, orally active agonist of the G protein-coupled bile acid receptor TGR5 (GPBAR1 or GPR131) with an EC50 of less than 1 μM. In mouse models, it demonstrates blood glucose-lowering effects, making it useful for diabetes research.
Molecular Formula
C37H59N2NaO9S
Molecular Weight
730.93
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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