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TGR5 agonist 7

Product Specifications

Target

GPCR19, Others

Related Pathways

Others, GPCR/G Protein

Bioactivity

TGR5 agonist 7 (Compound 22-Na) is an intestine-restricted, orally active agonist of the G protein-coupled bile acid receptor TGR5 (GPBAR1 or GPR131) with an EC50 of less than 1 μM. In mouse models, it demonstrates blood glucose-lowering effects, making it useful for diabetes research.

Molecular Formula

C37H59N2NaO9S

Molecular Weight

730.93

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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