Anticancer agent 260
Product Specifications
CAS Number
345994-70-9
Target
Reactive Oxygen Species
Related Pathways
Metabolism, NF-κB, Immunology/Inflammation
Bioactivity
Anticanceragent 260 (Compound 3g/4d) is an orally effective anticancer agent that inhibits the proliferation of cancer cells HCT-116, MIA-PaCa2, and MDA-MB231, with IC50 values of 98.7, 81.0, and 77.2 μg/mL, respectively. It also promotes ulcer formation and lipid peroxidation, and exhibits anti-inflammatory and analgesic activities.
Smiles
N=1N=C(OC1C=2C=CN=CC2)C=3C=CC=CC3C
Molecular Formula
C14H11N3O
Molecular Weight
237.26
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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