Euphjatrophane M
Product Specifications
Target
NF-κB, FOXO, Interleukin, TNF
Related Pathways
Immunology/Inflammation, Apoptosis, NF-κB
Bioactivity
Euphjatrophane M (Compound 6) is a FOXO1 inhibitor that reduces NF-κBp65 phosphorylation and exhibits anti-inflammatory properties. It can inhibit the production of nitric oxide and also suppress the mRNA expression of IL-6, IL-1β, and TNFα in LPS-induced RAW 264.7 macrophages.
Molecular Formula
C20H28O4
Molecular Weight
332.43
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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M28462-02 500 mg
6-chloro-1-ethyl-7- (4-methylpiperazin-1-yl) -4-oxo-1,4-dihydroquinoline-3-carboxylic acid
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M28462-03 5 mg
6-chloro-1-ethyl-7- (4-methylpiperazin-1-yl) -4-oxo-1,4-dihydroquinoline-3-carboxylic acid
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View Details M28462-04 10 mg
6-chloro-1-ethyl-7- (4-methylpiperazin-1-yl) -4-oxo-1,4-dihydroquinoline-3-carboxylic acid
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M28462-05 25 mg
6-chloro-1-ethyl-7- (4-methylpiperazin-1-yl) -4-oxo-1,4-dihydroquinoline-3-carboxylic acid
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View Details M28462-06 50 mg
6-chloro-1-ethyl-7- (4-methylpiperazin-1-yl) -4-oxo-1,4-dihydroquinoline-3-carboxylic acid
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View Details