Cladophorol A
Product Specifications
CAS Number
146776-30-9
Target
STING, cGAS
Related Pathways
Immunology/Inflammation
Bioactivity
Cladophorol A is a cGAS inhibitor that obstructs its activity by binding to the conserved adenosine nucleotide binding site of cGAS. It effectively suppresses the overactivation of the cGAS-STING pathway at non-cytotoxic concentrations, with an IC50 of 370 nM. Cladophorol A holds potential for research into inflammatory diseases linked to the overactivation of the cGAS-STING pathway.
Smiles
O=C1OC2=CC(O)=C(O)C=C2C=3C=C(O)C(O)=CC13
Molecular Formula
C13H8O6
Molecular Weight
260.2
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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