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CB2 receptor agonist 9

Product Specifications

CAS Number

2374894-21-8

Target

Cannabinoid Receptor

Related Pathways

GPCR/G Protein

Bioactivity

CB2 receptor agonist 9 (Compound 33) is an orally active agonist of cannabinoid receptor 2 (CB2 receptor) with an EC50 of 16.2 nM. It inhibits the expression of TNF-?, IL-1?, and IL-6, demonstrating anti-inflammatory activity in a DSS-induced acute colitis model in mice.

Smiles

O=C(NC(C)(C)CO)C1=NN(C(=C1)C=2SC=CC2)CCCC

Molecular Formula

C16H23N3O2S

Molecular Weight

321.44

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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