Sesaminol
Product Specifications
CAS Number
74061-79-3
Target
Nrf2|||Reactive Oxygen Species
Related Pathways
Metabolism|||NF-?B|||Immunology/Inflammation
Bioactivity
Sesaminol is an orally active activator of the Nrf2-ARE signaling pathway, promoting the nuclear translocation of Nrf2 and boosting the expression of NQO1 to enhance cellular defense against oxidative stress. It inhibits 6-OHDA-induced ROS production and apoptosis in SH-SY5Y cells. Sesaminol also provides neuroprotective effects against Rotenone-induced Parkinson's disease.
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OC1=C([C@@H]2[C@@]3([C@@]([C@H](OC3)C=4C=C5C(=CC4)OCO5)(CO2)[H])[H])C=C6C(=C1)OCO6
Molecular Formula
C20H18O7
Molecular Weight
370.35
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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